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IFNL3/4 genotype is associated with altered immune cell populations in peripheral blood in chronic hepatitis C infection
Single-nucleotide polymorphisms near the interferon lambda 3 (IFNL3) gene predict outcomes to infection and anti-viral treatment in hepatitis C virus (HCV) infection. To identify IFNL3 genotype effects on peripheral blood, we collected phenotype data on 400 patients with genotype 1 chronic hepatitis...
Autores principales: | O'Connor, K S, Read, S A, Wang, M, Schibeci, S, Eslam, M, Ong, A, Weltman, M D, Douglas, M W, Mazzola, A, Craxì, A, Petta, S, Stewart, G J, Liddle, C, George, J, Ahlenstiel, G, Booth, D R |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399140/ https://www.ncbi.nlm.nih.gov/pubmed/27307212 http://dx.doi.org/10.1038/gene.2016.27 |
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