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RUNX1/ETO blocks selectin-mediated adhesion via epigenetic silencing of PSGL-1

RUNX1/ETO (RE), the t(8;21)-derived leukemic transcription factor associated with acute myeloid leukemia (AML) development, deregulates genes involved in differentiation, self-renewal and proliferation. In addition, these cells show differences in cellular adhesion behavior whose molecular basis is...

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Detalles Bibliográficos
Autores principales:	Ponnusamy, K, Kohrs, N, Ptasinska, A, Assi, S A, Herold, T, Hiddemann, W, Lausen, J, Bonifer, C, Henschler, R, Wichmann, C
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399174/ https://www.ncbi.nlm.nih.gov/pubmed/25867177 http://dx.doi.org/10.1038/oncsis.2015.6

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