IRAK1 mediates TLR4-induced ABCA1 downregulation and lipid accumulation in VSMCs

The activation of Toll-like receptor 4 (TLR4) signaling has an important role in promoting lipid accumulation and pro-inflammatory effects in vascular smooth muscle cells (VSMCs), which facilitate atherosclerosis development and progression. Previous studies have demonstrated that excess lipid accum...

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Detalles Bibliográficos
Autores principales: Guo, L, Chen, C-H, Zhang, L-L, Cao, X-J, Ma, Q-L, Deng, P, Zhu, G, Gao, C-Y, Li, B-H, Pi, Y, Liu, Y, Hu, Z-C, Zhang, L, Yu, Z-P, Zhou, Z, Li, J-C
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399175/
https://www.ncbi.nlm.nih.gov/pubmed/26512959
http://dx.doi.org/10.1038/cddis.2015.212

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