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K(+) regulates Ca(2+) to drive inflammasome signaling: dynamic visualization of ion flux in live cells

P2X(7) purinergic receptor engagement with extracellular ATP induces transmembrane potassium and calcium flux resulting in assembly of the NLRP3 inflammasome in LPS-primed macrophages. The role of potassium and calcium in inflammasome regulation is not well understood, largely due to limitations in...

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Detalles Bibliográficos
Autores principales:	Yaron, J R, Gangaraju, S, Rao, M Y, Kong, X, Zhang, L, Su, F, Tian, Y, Glenn, H L, Meldrum, D R
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2015
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399176/ https://www.ncbi.nlm.nih.gov/pubmed/26512962 http://dx.doi.org/10.1038/cddis.2015.277

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