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The anticancer effect of chaetocin is enhanced by inhibition of autophagy

Chaetocin is a fungal metabolite that possesses a potent antiproliferative activity in solid tumors by inducing cell death. Although recent studies have extended the role of chaetocin in tumors, the underlying molecular mechanisms such as the downstream cascade that induces cell death has not clearl...

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Detalles Bibliográficos
Autores principales: Jung, H-J, Seo, I, Casciello, F, Jacquelin, S, Lane, S W, Suh, S-Il, Suh, M-H, Lee, J S, Baek, W-K
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399187/
https://www.ncbi.nlm.nih.gov/pubmed/26890137
http://dx.doi.org/10.1038/cddis.2016.15