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The anticancer effect of chaetocin is enhanced by inhibition of autophagy
Chaetocin is a fungal metabolite that possesses a potent antiproliferative activity in solid tumors by inducing cell death. Although recent studies have extended the role of chaetocin in tumors, the underlying molecular mechanisms such as the downstream cascade that induces cell death has not clearl...
Autores principales: | Jung, H-J, Seo, I, Casciello, F, Jacquelin, S, Lane, S W, Suh, S-Il, Suh, M-H, Lee, J S, Baek, W-K |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399187/ https://www.ncbi.nlm.nih.gov/pubmed/26890137 http://dx.doi.org/10.1038/cddis.2016.15 |
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