Neutrophil stunning by metoprolol reduces infarct size

The β1-adrenergic-receptor (ADRB1) antagonist metoprolol reduces infarct size in acute myocardial infarction (AMI) patients. The prevailing view has been that metoprolol acts mainly on cardiomyocytes. Here, we demonstrate that metoprolol reduces reperfusion injury by targeting the haematopoietic com...

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Detalles Bibliográficos
Autores principales: García-Prieto, Jaime, Villena-Gutiérrez, Rocío, Gómez, Mónica, Bernardo, Esther, Pun-García, Andrés, García-Lunar, Inés, Crainiciuc, Georgiana, Fernández-Jiménez, Rodrigo, Sreeramkumar, Vinatha, Bourio-Martínez, Rafael, García-Ruiz, José M, del Valle, Alfonso Serrano, Sanz-Rosa, David, Pizarro, Gonzalo, Fernández-Ortiz, Antonio, Hidalgo, Andrés, Fuster, Valentín, Ibanez, Borja
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399300/
https://www.ncbi.nlm.nih.gov/pubmed/28416795
http://dx.doi.org/10.1038/ncomms14780

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399300/
https://www.ncbi.nlm.nih.gov/pubmed/28416795
http://dx.doi.org/10.1038/ncomms14780

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