Heterogeneous ribonuclear protein A3 (hnRNP A3) is present in dipeptide repeat protein containing inclusions in Frontotemporal Lobar Degeneration and Motor Neurone disease associated with expansions in C9orf72 gene

Frontotemporal Lobar Degeneration (FTLD) encompasses certain related neurodegenerative disorders which alter behaviour, personality and language. Heterogeneous ribonuclear proteins (hnRNPs) maintain RNA metabolism and changes in their function may underpin the pathogenesis of FTLD. Immunostaining fo...

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Detalles Bibliográficos
Autores principales: Davidson, Yvonne S., Flood, Louis, Robinson, Andrew C., Nihei, Yoshihiro, Mori, Kohji, Rollinson, Sara, Richardson, Anna, Benson, Bridget C., Jones, Matthew, Snowden, Julie S., Pickering-Brown, Stuart, Haass, Christian, Lashley, Tammaryn, Mann, David M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399321/
https://www.ncbi.nlm.nih.gov/pubmed/28431575
http://dx.doi.org/10.1186/s40478-017-0437-5

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