CD200-positive cancer associated fibroblasts augment the sensitivity of Epidermal Growth Factor Receptor mutation-positive lung adenocarcinomas to EGFR Tyrosine kinase inhibitors

Cancer associated fibroblasts (CAFs) play important roles in the chemotherapeutic process, especially through influencing the resistance of tumor cells to molecular targeted therapy. Here we report the existence of a special subpopulation of patient-specific-CAFs that augment the sensitivity of EGFR...

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Detalles Bibliográficos
Autores principales: Ishibashi, Masayuki, Neri, Shinya, Hashimoto, Hiroko, Miyashita, Tomoyuki, Yoshida, Tatsuya, Nakamura, Yuka, Udagawa, Hibiki, Kirita, Keisuke, Matsumoto, Shingo, Umemura, Shigeki, Yoh, Kiyotaka, Niho, Seiji, Tsuboi, Masahiro, Masutomi, Kenkichi, Goto, Koichi, Ochiai, Atsushi, Ishii, Genichiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399371/
https://www.ncbi.nlm.nih.gov/pubmed/28429795
http://dx.doi.org/10.1038/srep46662

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