Anti-human platelet antigen (HPA)-1a antibodies may affect trophoblast functions crucial for placental development: a laboratory study using an in vitro model

BACKGROUND: Fetal and neonatal alloimmune thrombocytopenia (FNAIT) is a bleeding disorder caused by maternal antibodies against paternal human platelet antigens (HPAs) on fetal platelets. Antibodies against HPA-1a are accountable for the majority of FNAIT cases. We have previously shown that high le...

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Detalles Bibliográficos
Autores principales: Eksteen, Mariana, Heide, Gøril, Tiller, Heidi, Zhou, Yan, Nedberg, Nora Hersoug, Martinez-Zubiaurre, Inigo, Husebekk, Anne, Skogen, Bjørn R., Stuge, Tor B., Kjær, Mette
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399428/
https://www.ncbi.nlm.nih.gov/pubmed/28427432
http://dx.doi.org/10.1186/s12958-017-0245-6

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