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Vitamin D receptor, Retinoid X receptor and peroxisome proliferator-activated receptor γ are overexpressed in BRCA1 mutated breast cancer and predict prognosis

BACKGROUND: BRCA1 mutated breast cancers are commonly diagnosed as negative for classical hormone receptors i.e. estrogen receptor, progesterone receptor and/or Her2. Due to these common targets being absent the application of anti-endocrine therapies is rather limited and a certain focus has been s...

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Detalles Bibliográficos
Autores principales: Heublein, Sabine, Mayr, Doris, Meindl, Alfons, Kircher, Alexandra, Jeschke, Udo, Ditsch, Nina
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399435/
https://www.ncbi.nlm.nih.gov/pubmed/28427429
http://dx.doi.org/10.1186/s13046-017-0517-1

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