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Loss of pericyte smoothened activity in mice with genetic deficiency of leptin

BACKGROUND: Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage. Recovery from injury requires repair, an energy-expensive process that is coupled to energy availability at the cellular level. The satiety factor, leptin, is a key component o...

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Detalles Bibliográficos
Autores principales: Xie, Guanhua, Swiderska-Syn, Marzena, Jewell, Mark L., Machado, Mariana Verdelho, Michelotti, Gregory A., Premont, Richard T., Diehl, Anna Mae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399438/
https://www.ncbi.nlm.nih.gov/pubmed/28427343
http://dx.doi.org/10.1186/s12860-017-0135-y