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Loss of pericyte smoothened activity in mice with genetic deficiency of leptin
BACKGROUND: Obesity is associated with multiple diseases, but it is unclear how obesity promotes progressive tissue damage. Recovery from injury requires repair, an energy-expensive process that is coupled to energy availability at the cellular level. The satiety factor, leptin, is a key component o...
Autores principales: | Xie, Guanhua, Swiderska-Syn, Marzena, Jewell, Mark L., Machado, Mariana Verdelho, Michelotti, Gregory A., Premont, Richard T., Diehl, Anna Mae |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399438/ https://www.ncbi.nlm.nih.gov/pubmed/28427343 http://dx.doi.org/10.1186/s12860-017-0135-y |
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