Evaluation of a multi-arm multi-stage Bayesian design for phase II drug selection trials – an example in hemato-oncology

BACKGROUND: Multi-Arm Multi-Stage designs aim at comparing several new treatments to a common reference, in order to select or drop any treatment arm to move forward when such evidence already exists based on interim analyses. We redesigned a Bayesian adaptive design initially proposed for dose-find...

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Detalles Bibliográficos
Autores principales: Jacob, Louis, Uvarova, Maria, Boulet, Sandrine, Begaj, Inva, Chevret, Sylvie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399439/
https://www.ncbi.nlm.nih.gov/pubmed/27250349
http://dx.doi.org/10.1186/s12874-016-0166-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399439/
https://www.ncbi.nlm.nih.gov/pubmed/27250349
http://dx.doi.org/10.1186/s12874-016-0166-7

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