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Evaluation of a multi-arm multi-stage Bayesian design for phase II drug selection trials – an example in hemato-oncology
BACKGROUND: Multi-Arm Multi-Stage designs aim at comparing several new treatments to a common reference, in order to select or drop any treatment arm to move forward when such evidence already exists based on interim analyses. We redesigned a Bayesian adaptive design initially proposed for dose-find...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399439/ https://www.ncbi.nlm.nih.gov/pubmed/27250349 http://dx.doi.org/10.1186/s12874-016-0166-7 |