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A Formulated TLR7/8 Agonist is a Flexible, Highly Potent and Effective Adjuvant for Pandemic Influenza Vaccines
Since 1997, highly pathogenic avian influenza viruses of the H5N1 subtype have been transmitted from avian hosts to humans. The severity of H5N1 infection in humans, as well as the sporadic nature of H5N1 outbreaks, both geographically and temporally, make generation of an effective vaccine a global...
Autores principales: | Van Hoeven, Neal, Fox, Christopher B., Granger, Brian, Evers, Tara, Joshi, Sharvari W., Nana, Ghislain I., Evans, Sarah C., Lin, Susan, Liang, Hong, Liang, Li, Nakajima, Rie, Felgner, Philip L., Bowen, Richard A., Marlenee, Nicole, Hartwig, Airn, Baldwin, Susan L., Coler, Rhea N., Tomai, Mark, Elvecrog, James, Reed, Steven G., Carter, Darrick |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399443/ https://www.ncbi.nlm.nih.gov/pubmed/28429728 http://dx.doi.org/10.1038/srep46426 |
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