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Opossum APOBEC1 is a DNA mutator with retrovirus and retroelement restriction activity
APOBEC3s (A3s) are single-stranded DNA cytosine deaminases that provide innate immune defences against retroviruses and mobile elements. A3s are specific to eutherian mammals because no direct homologs exist at the syntenic genomic locus in metatherian (marsupial) or prototherian (monotreme) mammals...
Autores principales: | Ikeda, Terumasa, Shimoda, Mayuko, Ebrahimi, Diako, VandeBerg, John L., Harris, Reuben S., Koito, Atsushi, Maeda, Kazuhiko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399452/ https://www.ncbi.nlm.nih.gov/pubmed/28429755 http://dx.doi.org/10.1038/srep46719 |
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