Overexpression of mitochondrial oxodicarboxylate carrier (ODC1) preserves oxidative phosphorylation in a yeast model of Barth syndrome

Cardiolipin (CL) is a diglycerol phospholipid mostly found in mitochondria where it optimizes numerous processes, including oxidative phosphorylation (OXPHOS). To function properly, CL needs to be unsaturated, which requires the acyltransferase tafazzin. Loss-of-function mutations in this protein ar...

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Detalles Bibliográficos
Autores principales: de Taffin de Tilques, Maxence, Tribouillard-Tanvier, Déborah, Tétaud, Emmanuel, Testet, Eric, di Rago, Jean-Paul, Lasserre, Jean-Paul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399564/
https://www.ncbi.nlm.nih.gov/pubmed/28188263
http://dx.doi.org/10.1242/dmm.027540

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399564/
https://www.ncbi.nlm.nih.gov/pubmed/28188263
http://dx.doi.org/10.1242/dmm.027540

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