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A systems-level approach reveals new gene regulatory modules in the developing ear

The inner ear is a complex vertebrate sense organ, yet it arises from a simple epithelium, the otic placode. Specification towards otic fate requires diverse signals and transcriptional inputs that act sequentially and/or in parallel. Using the chick embryo, we uncover novel genes in the gene regula...

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Detalles Bibliográficos
Autores principales: Chen, Jingchen, Tambalo, Monica, Barembaum, Meyer, Ranganathan, Ramya, Simões-Costa, Marcos, Bronner, Marianne E., Streit, Andrea
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399671/
https://www.ncbi.nlm.nih.gov/pubmed/28264836
http://dx.doi.org/10.1242/dev.148494