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Effects of the common polymorphism in the human aldehyde dehydrogenase 2 (ALDH2) gene on the lung

BACKGROUND: Aldehyde dehydrogenases (ALDHs) play a major role in detoxification of aldehydes. High expression of ALDHs is a marker for stem cells of many organs including the lungs. A common polymorphism in ALDH2 gene (ALDH2*2) results in inactivation of the enzyme and is associated with alcohol flu...

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Detalles Bibliográficos
Autores principales:	Kuroda, Aoi, Hegab, Ahmed E., Jingtao, Gao, Yamashita, Shuji, Hizawa, Nobuyuki, Sakamoto, Tohru, Yamada, Hideyasu, Suzuki, Satoshi, Ishii, Makoto, Namkoong, Ho, Asakura, Takanori, Ozaki, Mari, Yasuda, Hiroyuki, Hamamoto, Junko, Kagawa, Shizuko, Soejima, Kenzo, Betsuyaku, Tomoko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2017
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399815/ https://www.ncbi.nlm.nih.gov/pubmed/28431562 http://dx.doi.org/10.1186/s12931-017-0554-5

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