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Sharp bounds on sufficient-cause interactions under the assumption of no redundancy
BACKGROUND: Sufficient-cause interaction is a type of interaction that has received much attention recently. The sufficient component cause model on which the sufficient-cause interaction is based is however a non-identifiable model. Estimating the interaction parameters from the model is mathematic...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2017
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399844/ https://www.ncbi.nlm.nih.gov/pubmed/28431517 http://dx.doi.org/10.1186/s12874-017-0348-y |
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author | Lee, Wen-Chung |
author_facet | Lee, Wen-Chung |
author_sort | Lee, Wen-Chung |
collection | PubMed |
description | BACKGROUND: Sufficient-cause interaction is a type of interaction that has received much attention recently. The sufficient component cause model on which the sufficient-cause interaction is based is however a non-identifiable model. Estimating the interaction parameters from the model is mathematically impossible. METHODS: In this paper, I derive bounding formulae for sufficient-cause interactions under the assumption of no redundancy. RESULTS: Two real data sets are used to demonstrate the method (R codes provided). The proposed bounds are sharp and sharper than previous bounds. CONCLUSIONS: Sufficient-cause interactions can be quantified by setting bounds on them. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12874-017-0348-y) contains supplementary material, which is available to authorized users. |
format | Online Article Text |
id | pubmed-5399844 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2017 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-53998442017-04-24 Sharp bounds on sufficient-cause interactions under the assumption of no redundancy Lee, Wen-Chung BMC Med Res Methodol Research Article BACKGROUND: Sufficient-cause interaction is a type of interaction that has received much attention recently. The sufficient component cause model on which the sufficient-cause interaction is based is however a non-identifiable model. Estimating the interaction parameters from the model is mathematically impossible. METHODS: In this paper, I derive bounding formulae for sufficient-cause interactions under the assumption of no redundancy. RESULTS: Two real data sets are used to demonstrate the method (R codes provided). The proposed bounds are sharp and sharper than previous bounds. CONCLUSIONS: Sufficient-cause interactions can be quantified by setting bounds on them. ELECTRONIC SUPPLEMENTARY MATERIAL: The online version of this article (doi:10.1186/s12874-017-0348-y) contains supplementary material, which is available to authorized users. BioMed Central 2017-04-21 /pmc/articles/PMC5399844/ /pubmed/28431517 http://dx.doi.org/10.1186/s12874-017-0348-y Text en © The Author(s). 2017 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. |
spellingShingle | Research Article Lee, Wen-Chung Sharp bounds on sufficient-cause interactions under the assumption of no redundancy |
title | Sharp bounds on sufficient-cause interactions under the assumption of no redundancy |
title_full | Sharp bounds on sufficient-cause interactions under the assumption of no redundancy |
title_fullStr | Sharp bounds on sufficient-cause interactions under the assumption of no redundancy |
title_full_unstemmed | Sharp bounds on sufficient-cause interactions under the assumption of no redundancy |
title_short | Sharp bounds on sufficient-cause interactions under the assumption of no redundancy |
title_sort | sharp bounds on sufficient-cause interactions under the assumption of no redundancy |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399844/ https://www.ncbi.nlm.nih.gov/pubmed/28431517 http://dx.doi.org/10.1186/s12874-017-0348-y |
work_keys_str_mv | AT leewenchung sharpboundsonsufficientcauseinteractionsundertheassumptionofnoredundancy |