Cargando…

Metformin ameliorates insulitis in STZ-induced diabetic mice

BACKGROUND & AIMS: Metformin is currently the most widely used first-line hypoglycemic agent for diabetes mellitus. Besides glucose-lowering action, there is increasingly interest in the potential anti-inflammatory action of this drug. In the present study, we investigated the actions of metform...

Descripción completa

Detalles Bibliográficos
Autores principales:	Han, Xue, Tao, Yu-Long, Deng, Ya-Ping, Yu, Jia-Wen, Cai, Jian, Ren, Guo-Fei, Sun, Yuan-Nan, Jiang, Guo-Jun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	PeerJ Inc. 2017
Materias:	Diabetes and Endocrinology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399881/ https://www.ncbi.nlm.nih.gov/pubmed/28439456 http://dx.doi.org/10.7717/peerj.3155

Ejemplares similares

Acarbose-metformin is more effective in glycemic variability control than repaglinide-metformin in T2DM patients inadequately controlled with metformin: a retrospective cohort study
por: Du, Guoli, et al.
Publicado: (2020)

Effect of metformin monotherapy on serum lipid profile in statin-naïve individuals with newly diagnosed type 2 diabetes mellitus: a cohort study
por: Lin, Szu Han, et al.
Publicado: (2018)

Treatment pathways in people with type 2 diabetes mellitus: a nationwide cohort study of new users of metformin monotherapy in New Zealand
por: Guo, Joyce, et al.
Publicado: (2021)

Metformin versus placebo in combination with insulin analogues in patients with type 2 diabetes mellitus—the randomised, blinded Copenhagen Insulin and Metformin Therapy (CIMT) trial
por: Lundby-Christensen, Louise, et al.
Publicado: (2016)

An investigation into the therapeutic effects of statins with metformin on polycystic ovary syndrome: a meta-analysis of randomised controlled trials
por: Sun, Jie, et al.
Publicado: (2015)

Metformin initiation and renal impairment: a cohort study in Denmark and the UK
por: Christiansen, Christian Fynbo, et al.
Publicado: (2015)

Metformin improves the angiogenic functions of endothelial progenitor cells via activating AMPK/eNOS pathway in diabetic mice
por: Yu, Jia-Wen, et al.
Publicado: (2016)

Benefits of Huang Lian mediated by gut microbiota on HFD/STZ-induced type 2 diabetes mellitus in mice
por: Li, Dan, et al.
Publicado: (2023)

Effect of metformin on neurodegenerative disease among elderly adult US veterans with type 2 diabetes mellitus
por: Shi, Qian, et al.
Publicado: (2019)

Effects of metformin on bone mineral density and bone turnover markers: a systematic review and meta-analysis
por: Hu, Jinhua, et al.
Publicado: (2023)

Metformin Use and Metformin-associated Lactic Acidosis in Intensive Care Unit Patients with Diabetes
por: Rajasurya, Venkat, et al.
Publicado: (2019)

A glucagon-like peptide-1 analog, liraglutide, ameliorates endothelial dysfunction through miRNAs to inhibit apoptosis in rats
por: Zhang, Qian, et al.
Publicado: (2019)

Low level light therapy/photobiomodulation for diabetic peripheral neuropathy: protocol of a systematic review and meta-analysis
por: Wang, Jia-You, et al.
Publicado: (2022)

Metformin-Induced Acute Hepatitis
por: Mian, Arooj, et al.
Publicado: (2023)

Identifying prevalence and risk factors for metformin non-persistence: a retrospective cohort study using an electronic health record
por: Flory, James H, et al.
Publicado: (2018)

Polyphenol-rich Trapa quadrispinosa pericarp extract ameliorates high-fat diet induced non-alcoholic fatty liver disease by regulating lipid metabolism and insulin resistance in mice
por: Jian, Tunyu, et al.
Publicado: (2019)

Effectiveness of sitagliptin compared to sulfonylureas for type 2 diabetes mellitus inadequately controlled on metformin: a systematic review and meta-analysis
por: Sharma, Manuj, et al.
Publicado: (2017)

Prevalence of Vitamin B12 Deficiency in Patients with Type II Diabetes Mellitus on Metformin: A Study from Khyber Pakhtunkhwa
por: Khan, Adnan, et al.
Publicado: (2017)

Metformin discontinuation in patients beginning second-line glucose-lowering therapy: results from the global observational DISCOVER study programme
por: Khunti, Kamlesh, et al.
Publicado: (2020)

Protocol for a randomised controlled trial of the effect of dapagliflozin, metformin and exercise on glycaemic variability, body composition and cardiovascular risk in prediabetes (the PRE-D Trial)
por: Færch, Kristine, et al.
Publicado: (2017)

Rationale and design of a randomised controlled trial testing the effect of personalised diet in individuals with pre-diabetes or type 2 diabetes mellitus treated with metformin
por: Htet, Thaw D, et al.
Publicado: (2020)

Metformin-associated Lactic Acidosis: An Unexpected Scenario
por: Asif, Samia, et al.
Publicado: (2019)

The Future of Metformin in the Prevention of Diabetes-Related Osteoporosis
por: Aung, Myat, et al.
Publicado: (2020)

A Case of Metformin-Associated Lactic Acidosis
por: Mahmood, Rabia, et al.
Publicado: (2023)

Comparative efficacy and safety of statins for osteoporosis: a study protocol for a systematic review and network meta-analysis
por: Xiong, Mengxin, et al.
Publicado: (2022)

The modern spectrum of biopsy-proven renal disease in Chinese diabetic patients—a retrospective descriptive study
por: Liu, Diankun, et al.
Publicado: (2018)

Pregnancy Outcomes: Effects of Metformin (POEM) study: a protocol for a long-term, multicentre, open-label, randomised controlled trial in gestational diabetes mellitus
por: van Hoorn, Eline G M, et al.
Publicado: (2022)

Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register
por: Ekström, Nils, et al.
Publicado: (2012)

Reactive Hypoglycemia From Metformin Immediate-Release Monotherapy Resolved by a Switch to Metformin Extended-Release: Conceptualizing Their Concentration-Time Curves
por: Akram, Ayesha
Publicado: (2021)

Metformin-Induced Lactic Acidosis: A Case Study
por: Chowdhury, Waliul, et al.
Publicado: (2018)

A Case Report on Metformin-Associated Lactic Acidosis
por: Rai, Harpreet K, et al.
Publicado: (2020)

Acupuncture or metformin to improve insulin resistance in women with polycystic ovary syndrome: study protocol of a combined multinational cross sectional case-control study and a randomised controlled trial
por: Stener-Victorin, Elisabet, et al.
Publicado: (2019)

Effects of biphasic, basal-bolus or basal insulin analogue treatments on carotid intima-media thickness in patients with type 2 diabetes mellitus: the randomised Copenhagen Insulin and Metformin Therapy (CIMT) trial
por: Lundby-Christensen, Louise, et al.
Publicado: (2016)

Hand grip strength is inversely associated with total daily insulin dose requirement in patients with type 2 diabetes mellitus: a cross-sectional study
por: Chen, Da-shuang, et al.
Publicado: (2023)

Metformin-Associated Lactic Acidosis: A Case Report and Review
por: Ashraf, Shoaib, et al.
Publicado: (2022)

Metformin and other glucose-lowering drug initiation and rates of community-based antibiotic use and hospital-treated infections in patients with type 2 diabetes: a Danish nationwide population-based cohort study
por: Mor, Anil, et al.
Publicado: (2016)

Comparison of the effects on cardiovascular events between use of metformin and dipeptidyl peptidase-4 inhibitors as the first-line hypoglycaemic agents in Japanese patients with type 2 diabetes mellitus: a claims database analysis
por: Nishimura, Rimei, et al.
Publicado: (2022)

Metformin in the prevention of type 2 diabetes after gestational diabetes in postnatal women (OMAhA): a UK multicentre randomised, placebo-controlled, double-blind feasibility trial with nested qualitative study
por: Bolou, Angeliki, et al.
Publicado: (2023)

Association of liver enzymes levels with fasting plasma glucose levels in Southern China: a cross-sectional study
por: Huang, Ling-Ling, et al.
Publicado: (2019)

IL-33 Prevents MLD-STZ Induction of Diabetes and Attenuate Insulitis in Prediabetic NOD Mice
por: Pavlovic, Sladjana, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_5nrs05ob8j0j43t40en0sbjnu3