DNA nanochannels

Transmembrane proteins are mostly nanochannels playing a highly important role in metabolism. Understanding their structures and functions is vital for revealing life processes. It is of fundamental interest to develop chemical devices to mimic biological channels. Structural DNA nanotechnology has...

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Detalles Bibliográficos
Autores principales: Wang, Dianming, Zhang, Yiyang, Liu, Dongsheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2017
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399953/
https://www.ncbi.nlm.nih.gov/pubmed/28491290
http://dx.doi.org/10.12688/f1000research.10464.1
Descripción
Sumario:Transmembrane proteins are mostly nanochannels playing a highly important role in metabolism. Understanding their structures and functions is vital for revealing life processes. It is of fundamental interest to develop chemical devices to mimic biological channels. Structural DNA nanotechnology has been proven to be a promising method for the preparation of fine DNA nanochannels as a result of the excellent properties of DNA molecules. This review presents the development history and current situation of three different types of DNA nanochannel: tile-based nanotube, DNA origami nanochannel, and DNA bundle nanochannel.

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