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Effects of CYP2D6 and CYP3A5 polymorphisms on tamoxifen and its metabolites in Thai breast cancer patients

PURPOSE: This study aimed to determine the effects of CYP2D6 and CYP3A5 polymorphisms on the levels of tamoxifen (TAM) and its metabolites in the plasma of breast cancer patients. The protocol was designed to test the associations between CYP2D6, CYP3A5 genotypes and phenotypes (extensive metabolize...

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Detalles Bibliográficos
Autores principales:	Charoenchokthavee, Wanaporn, Areepium, Nutthada, Panomvana, Duangchit, Sriuranpong, Virote
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Dove Medical Press 2017
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399972/ https://www.ncbi.nlm.nih.gov/pubmed/28450788 http://dx.doi.org/10.2147/BCTT.S125745

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