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Chitosan nanoparticle-based delivery of fused NKG2D–IL-21 gene suppresses colon cancer growth in mice

Nanoparticles can be loaded with exogenous DNA for the potential expression of cytokines with immune-stimulatory function. NKG2D identifies major histocompatibility complex class I chain-related protein in human and retinoic acid early induced transcript-1 in mouse, which acts as tumor-associated an...

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Detalles Bibliográficos
Autores principales: Tan, Lunmei, Han, Sen, Ding, Shizhen, Xiao, Weiming, Ding, Yanbing, Qian, Li, Wang, Chenming, Gong, Weijuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399983/
https://www.ncbi.nlm.nih.gov/pubmed/28450784
http://dx.doi.org/10.2147/IJN.S128032

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