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Chitosan nanoparticle-based delivery of fused NKG2D–IL-21 gene suppresses colon cancer growth in mice
Nanoparticles can be loaded with exogenous DNA for the potential expression of cytokines with immune-stimulatory function. NKG2D identifies major histocompatibility complex class I chain-related protein in human and retinoic acid early induced transcript-1 in mouse, which acts as tumor-associated an...
Autores principales: | Tan, Lunmei, Han, Sen, Ding, Shizhen, Xiao, Weiming, Ding, Yanbing, Qian, Li, Wang, Chenming, Gong, Weijuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5399983/ https://www.ncbi.nlm.nih.gov/pubmed/28450784 http://dx.doi.org/10.2147/IJN.S128032 |
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