Cargando…

Genome-wide genetic analyses highlight mitogen-activated protein kinase (MAPK) signaling in the pathogenesis of endometriosis

STUDY QUESTION: Do genome-wide association study (GWAS) data for endometriosis provide insight into novel biological pathways associated with its pathogenesis? SUMMARY ANSWER: GWAS analysis uncovered multiple pathways that are statistically enriched for genetic association signals, analysis of Stage...

Descripción completa

Detalles Bibliográficos
Autores principales:	Uimari, Outi, Rahmioglu, Nilufer, Nyholt, Dale R., Vincent, Katy, Missmer, Stacey A., Becker, Christian, Morris, Andrew P., Montgomery, Grant W., Zondervan, Krina T.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Original Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400041/ https://www.ncbi.nlm.nih.gov/pubmed/28333195 http://dx.doi.org/10.1093/humrep/dex024

Ejemplares similares

Genetic variants underlying risk of endometriosis: insights from meta-analysis of eight genome-wide association and replication datasets
por: Rahmioglu, Nilufer, et al.
Publicado: (2014)

Insights into Assessing the Genetics of Endometriosis
por: Rahmioglu, Nilufer, et al.
Publicado: (2012)

Genome-wide enrichment analysis between endometriosis and obesity-related traits reveals novel susceptibility loci
por: Rahmioglu, Nilufer, et al.
Publicado: (2015)

Evidence of a causal effect of genetic tendency to gain muscle mass on uterine leiomyomata
por: Sliz, Eeva, et al.
Publicado: (2023)

World Endometriosis Research Foundation Endometriosis Phenome and biobanking harmonization project: II. Clinical and covariate phenotype data collection in endometriosis research
por: Vitonis, Allison F., et al.
Publicado: (2014)

The association between endometriosis and autoimmune diseases: a systematic review and meta-analysis
por: Shigesi, Nina, et al.
Publicado: (2019)

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: IV. Tissue collection, processing, and storage in endometriosis research
por: Fassbender, Amelie, et al.
Publicado: (2014)

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project: III. Fluid biospecimen collection, processing, and storage in endometriosis research
por: Rahmioglu, Nilufer, et al.
Publicado: (2014)

Protocol for the Cultural Translation and Adaptation of the World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonization Project Endometriosis Participant Questionnaire (EPHect)
por: Mis, Cise, et al.
Publicado: (2021)

The miRNA Mirage: How Close Are We to Finding a Non-Invasive Diagnostic Biomarker in Endometriosis? A Systematic Review
por: Agrawal, Swati, et al.
Publicado: (2018)

Impact of Endometriosis in Women of Arab Ancestry on: Health-Related Quality of Life, Work Productivity, and Diagnostic Delay
por: Mousa, Mira, et al.
Publicado: (2021)

World Endometriosis Research Foundation Endometriosis Phenome and Biobanking Harmonisation Project: I. Surgical phenotype data collection in endometriosis research
por: Becker, Christian M., et al.
Publicado: (2014)

Prevalence of Common Gynecological Conditions in the Middle East: Systematic Review and Meta-Analysis
por: Mousa, Mira, et al.
Publicado: (2021)

Meta-analysis identifies five novel loci associated with endometriosis highlighting key genes involved in hormone metabolism
por: Sapkota, Yadav, et al.
Publicado: (2017)

No evidence for genetic association with the let-7 microRNA-binding site or other common KRAS variants in risk of endometriosis
por: Luong, Hien T.T., et al.
Publicado: (2012)

The role of gene polymorphisms in endometriosis
por: Matalliotakis, Michail, et al.
Publicado: (2017)

Estimation and partitioning of polygenic variation captured by common SNPs for Alzheimer's disease, multiple sclerosis and endometriosis
por: Lee, S. Hong, et al.
Publicado: (2013)

The role of IL-16 gene polymorphisms in endometriosis
por: Matalliotakis, Michail, et al.
Publicado: (2018)

Role of FN1 and GREB1 gene polymorphisms in endometriosis
por: Matalliotaki, Charoula, et al.
Publicado: (2019)

The influence of menstrual cycle and endometriosis on endometrial methylome
por: Saare, Merli, et al.
Publicado: (2016)

Predictors and trends of Caesarean section and breastfeeding in the Eastern Mediterranean region: Data from the cross-sectional Cyprus Women’s Health Research (COHERE) Initiative
por: Swift, Bethan, et al.
Publicado: (2023)

Genome-wide association study identifies a locus at 7p15.2 associated with endometriosis
por: Painter, Jodie N., et al.
Publicado: (2010)

Genome-wide association meta-analysis identifies new endometriosis risk loci
por: Nyholt, Dale R., et al.
Publicado: (2012)

Editorial: Highlights in gynecology 2021/22
por: Buggio, Laura, et al.
Publicado: (2023)

An international terminology for endometriosis, 2021(,)
por: Tomassetti, Carla, et al.
Publicado: (2021)

Endometriosis classification, staging and reporting systems: a review on the road to a universally accepted endometriosis classification(,)
por: Vermeulen, Nathalie, et al.
Publicado: (2021)

A Simple and Fast Two-Locus Quality Control Test to Detect False Positives Due to Batch Effects in Genome-Wide Association Studies
por: Lee, Sang Hong, et al.
Publicado: (2010)

Do symptomatic endometriosis and uterine fibroids appear together?
por: Uimari, Outi, et al.
Publicado: (2011)

Endometriosis and Uterine Fibroids (Leiomyomata): Comorbidity, Risks and Implications
por: Uimari, Outi, et al.
Publicado: (2021)

Endometriosis classification systems: an international survey to map current knowledge and uptake(†)(‡)
por: Zondervan, Krina T, et al.
Publicado: (2022)

Large-scale meta-analysis highlights the hypothalamic–pituitary–gonadal axis in the genetic regulation of menstrual cycle length
por: Laisk, Triin, et al.
Publicado: (2018)

Global endometrial DNA methylation analysis reveals insights into mQTL regulation and associated endometriosis disease risk and endometrial function
por: Mortlock, Sally, et al.
Publicado: (2023)

The Global Impact of COVID-19 on the Care of People With Endometriosis
por: Demetriou, Lysia, et al.
Publicado: (2021)

Priorities for Endometriosis Research: Recommendations From an International Consensus Workshop
por: Rogers, Peter A. W., et al.
Publicado: (2009)

Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
por: Gallagher, C. S., et al.
Publicado: (2019)

Obesity and risk of female reproductive conditions: A Mendelian randomisation study
por: Venkatesh, Samvida S., et al.
Publicado: (2022)

Correction: Obesity and risk of female reproductive conditions: A Mendelian randomisation study
por: Venkatesh, Samvida S., et al.
Publicado: (2022)

Stressful experiences impact clinical symptoms in people with endometriosis
por: Demetriou, Lysia, et al.
Publicado: (2022)

Author Correction: Genome-wide association and epidemiological analyses reveal common genetic origins between uterine leiomyomata and endometriosis
por: Gallagher, C. S., et al.
Publicado: (2022)

Characterization of exosomes in peritoneal fluid of endometriosis patients
por: Nazri, Hannah M., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_acsios64cosptadt8p99n0k67v