Rapid accumulation of HIV-1 thymidine analogue mutations and phenotypic impact following prolonged viral failure on zidovudine-based first-line ART in sub-Saharan Africa

Background: Lack of viral load monitoring of ART is known to be associated with slower switch from a failing regimen and thereby higher prevalence of MDR HIV-1. Many countries have continued to use thymidine analogue drugs despite recommendations to use tenofovir in combination with a cytosine analo...

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Detalles Bibliográficos
Autores principales: Goodall, Ruth L., Dunn, David T., Nkurunziza, Peter, Mugarura, Lincoln, Pattery, Theresa, Munderi, Paula, Kityo, Cissy, Gilks, Charles, Kaleebu, Pontiano, Pillay, Deenan, Gupta, Ravindra K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400089/
https://www.ncbi.nlm.nih.gov/pubmed/28160504
http://dx.doi.org/10.1093/jac/dkw583

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