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Polymorphix: a sequence polymorphism database

Within-species sequence variation data are of special interest since they contain information about recent population/species history, and the molecular evolutionary forces currently in action in natural populations. These data, however, are presently dispersed within generalist databases, and are d...

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Detalles Bibliográficos
Autores principales: Bazin, Eric, Duret, Laurent, Penel, Simon, Galtier, Nicolas
Formato: Texto
Lenguaje:English
Publicado: Oxford University Press 2005
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC540030/
https://www.ncbi.nlm.nih.gov/pubmed/15608242
http://dx.doi.org/10.1093/nar/gki076
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author Bazin, Eric
Duret, Laurent
Penel, Simon
Galtier, Nicolas
author_facet Bazin, Eric
Duret, Laurent
Penel, Simon
Galtier, Nicolas
author_sort Bazin, Eric
collection PubMed
description Within-species sequence variation data are of special interest since they contain information about recent population/species history, and the molecular evolutionary forces currently in action in natural populations. These data, however, are presently dispersed within generalist databases, and are difficult to access. To solve this problem, we have developed Polymorphix, a database dedicated to sequence polymorphism. It contains within-species homologous sequence families built using EMBL/GenBank under suitable similarity and bibliographic criteria. Polymorphix is an ACNUC structured database allowing both simple and complex queries for population genomic studies. Alignments within families as well as phylogenetic trees can be download. When available, outgroups are included in the alignment. Polymorphix contains sequences from the nuclear, mitochondrial and chloroplastic genomes of every eukaryote species represented in EMBL. It can be accessed by a web interface (http://pbil.univ-lyon1.fr/polymorphix/query.php).
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spelling pubmed-5400302005-01-04 Polymorphix: a sequence polymorphism database Bazin, Eric Duret, Laurent Penel, Simon Galtier, Nicolas Nucleic Acids Res Articles Within-species sequence variation data are of special interest since they contain information about recent population/species history, and the molecular evolutionary forces currently in action in natural populations. These data, however, are presently dispersed within generalist databases, and are difficult to access. To solve this problem, we have developed Polymorphix, a database dedicated to sequence polymorphism. It contains within-species homologous sequence families built using EMBL/GenBank under suitable similarity and bibliographic criteria. Polymorphix is an ACNUC structured database allowing both simple and complex queries for population genomic studies. Alignments within families as well as phylogenetic trees can be download. When available, outgroups are included in the alignment. Polymorphix contains sequences from the nuclear, mitochondrial and chloroplastic genomes of every eukaryote species represented in EMBL. It can be accessed by a web interface (http://pbil.univ-lyon1.fr/polymorphix/query.php). Oxford University Press 2005-01-01 2004-12-17 /pmc/articles/PMC540030/ /pubmed/15608242 http://dx.doi.org/10.1093/nar/gki076 Text en Copyright © 2005 Oxford University Press
spellingShingle Articles
Bazin, Eric
Duret, Laurent
Penel, Simon
Galtier, Nicolas
Polymorphix: a sequence polymorphism database
title Polymorphix: a sequence polymorphism database
title_full Polymorphix: a sequence polymorphism database
title_fullStr Polymorphix: a sequence polymorphism database
title_full_unstemmed Polymorphix: a sequence polymorphism database
title_short Polymorphix: a sequence polymorphism database
title_sort polymorphix: a sequence polymorphism database
topic Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC540030/
https://www.ncbi.nlm.nih.gov/pubmed/15608242
http://dx.doi.org/10.1093/nar/gki076
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