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Thymoma (World Health Organization type B3) with neuroendocrine differentiation in multiple endocrine neoplasia type 1

Thymic epithelial tumors occur in 1–5% of patients with multiple endocrine neoplasia type 1 (MEN 1). Majority of these thymic epithelial tumors are thymic carcinoids and patients with thymoma in MEN 1 is rare. Furthermore, thymoma with neuroendocrine differentiation was also rarely reported. Herein,...

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Detalles Bibliográficos
Autores principales: Tomita, Masaki, Ichiki, Nobuhiko, Ayabe, Takanori, Tanaka, Hiroyuki, Kataoka, Hiroaki, Nakamura, Kunihide
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400497/
https://www.ncbi.nlm.nih.gov/pubmed/28458876
http://dx.doi.org/10.1093/jscr/rjx071
Descripción
Sumario:Thymic epithelial tumors occur in 1–5% of patients with multiple endocrine neoplasia type 1 (MEN 1). Majority of these thymic epithelial tumors are thymic carcinoids and patients with thymoma in MEN 1 is rare. Furthermore, thymoma with neuroendocrine differentiation was also rarely reported. Herein, we report a 68-year-old man having type B3 thymoma with neuroendocrine differentiation in MEN 1 and to the best of our knowledge this is the first such case ever reported.