Cargando…

Lipid and Alzheimer’s disease genes associated with healthy aging and longevity in healthy oldest-old

Several studies have found that long-lived individuals do not appear to carry lower numbers of common disease-associated variants than ordinary people; it has been hypothesized that they may instead carry protective variants. An intriguing type of protective variant is buffering variants that protec...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tindale, Lauren C., Leach, Stephen, Spinelli, John J., Brooks-Wilson, Angela R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper: Gerotarget (Focus on Aging)
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400530/ https://www.ncbi.nlm.nih.gov/pubmed/28206976 http://dx.doi.org/10.18632/oncotarget.15296

Ejemplares similares

Weight loss in the healthy elderly might be a non-cognitive sign of preclinical Alzheimer's disease
por: Jimenez, Amanda, et al.
Publicado: (2017)

Effect of HMGCR genetic variation on neuroimaging biomarkers in healthy, mild cognitive impairment and Alzheimer's disease cohorts
por: Cao, Lei, et al.
Publicado: (2016)

The rate of change in declining steroid hormones: a new parameter of healthy aging in men?
por: Walther, Andreas, et al.
Publicado: (2016)

Non-coding genomic regions possessing enhancer and silencer potential are associated with healthy aging and exceptional survival
por: Kim, Sangkyu, et al.
Publicado: (2015)

Age-related modulation of plasmatic beta-Galactosidase activity in healthy subjects and in patients affected by T2DM
por: Spazzafumo, Liana, et al.
Publicado: (2017)

Influence of non-steroidal anti-inflammatory drugs on Drosophila melanogaster longevity
por: Danilov, Anton, et al.
Publicado: (2015)

APOE-by-sex interactions on brain structure and metabolism in healthy elderly controls
por: Sampedro, Frederic, et al.
Publicado: (2015)

Safety of two-year caloric restriction in non-obese healthy individuals
por: Romashkan, Sergei V., et al.
Publicado: (2016)

IGF-1 mediated phosphorylation of specific IRS-1 serines in Ames dwarf fibroblasts is associated with longevity
por: Papaconstantinou, John, et al.
Publicado: (2015)

Nitrogen and carbon source balance determines longevity, independently of fermentative or respiratory metabolism in the yeast Saccharomyces cerevisiae
por: Santos, Júlia, et al.
Publicado: (2016)

Reprogramming of energy metabolism as a driver of aging
por: Feng, Zhaoyang, et al.
Publicado: (2016)

CGEF-1 regulates mTORC1 signaling during adult longevity and stress response in C. elegans
por: Li, Yujie, et al.
Publicado: (2018)

Common DNA methylation alterations of Alzheimer's disease and aging in peripheral whole blood
por: Li, Hongdong, et al.
Publicado: (2016)

Methylomic predictors demonstrate the role of NF-κB in old-age mortality and are unrelated to the aging-associated epigenetic drift
por: Jylhävä, Juulia, et al.
Publicado: (2016)

Association study of polymorphisms in FOXO3, AKT1 and IGF-2R genes with human longevity in a Han Chinese population
por: Li, Ning, et al.
Publicado: (2015)

Effects of circadian clock genes and environmental factors on cognitive aging in old adults in a Taiwanese population
por: Lin, Eugene, et al.
Publicado: (2017)

DNA damage response (DDR) and senescence: shuttled inflamma-miRNAs on the stage of inflamm-aging
por: Olivieri, Fabiola, et al.
Publicado: (2015)

Effects of eight weeks of aerobic interval training and of isoinertial resistance training on risk factors of cardiometabolic diseases and exercise capacity in healthy elderly subjects
por: Bruseghini, Paolo, et al.
Publicado: (2015)

Environmental tobacco smoke increases autophagic effects but decreases longevity associated with Sirt-1 protein expression in young C57BL mice hearts
por: Ting, Wei-Jen, et al.
Publicado: (2016)

Genetics of healthy aging and longevity
por: Brooks-Wilson, Angela R.
Publicado: (2013)

Association and interaction effects of Alzheimer’s disease-associated genes and lifestyle on cognitive aging in older adults in a Taiwanese population
por: Lin, Eugene, et al.
Publicado: (2017)

Genetic Variation in Healthy Oldest-Old
por: Halaschek-Wiener, Julius, et al.
Publicado: (2009)

Dietary patterns in the healthy oldest old in the healthy aging study and the Canadian longitudinal study of aging: a cohort study
por: Gu, Qianqian, et al.
Publicado: (2020)

mTORC2 takes the longevity stAGE
por: Lamming, Dudley W.
Publicado: (2014)

Allele-Specific Transcript Abundance: A Pilot Study in Healthy Centenarians
por: Tindale, Lauren C, et al.
Publicado: (2020)

Dynamic self-guiding analysis of Alzheimer's disease
por: Kurakin, Alexei, et al.
Publicado: (2015)

VGF expression by T lymphocytes in patients with Alzheimer's disease
por: Busse, Stefan, et al.
Publicado: (2015)

Serotonin 6 receptor controls alzheimer’s disease and depression
por: Yun, Hyung-Mun, et al.
Publicado: (2015)

Identification of prefrontal cortex protein alterations in Alzheimer’s disease
por: Garranzo-Asensio, Maria, et al.
Publicado: (2018)

Fluoxetine attenuates the impairment of spatial learning ability and prevents neuron loss in middle-aged APPswe/PSEN1dE9 double transgenic Alzheimer's disease mice
por: Ma, Jing, et al.
Publicado: (2017)

Olfactory bulb proteome dynamics during the progression of sporadic Alzheimer's disease: identification of common and distinct olfactory targets across Alzheimer-related co-pathologies
por: Zelaya, María Victoria, et al.
Publicado: (2015)

RCAN1 in the inverse association between Alzheimer’s disease and cancer
por: Fu, Qiang, et al.
Publicado: (2017)

FRAILTY IN HEALTHY OLDEST OLD: CHARACTERIZING THE FRAILTY INDEX OF SUPER-SENIORS
por: Chinda, Betty, et al.
Publicado: (2019)

Vaccine efficacy and T helper cell differentiation change with aging
por: Lefebvre, Julie S., et al.
Publicado: (2016)

Consumption of pomegranates improves synaptic function in a transgenic mice model of Alzheimer's disease
por: Braidy, Nady, et al.
Publicado: (2016)

Immunostimulatory effects of RACK1 pseudosubstrate in human leukocytes obtained from young and old donors
por: Corsini, Emanuela, et al.
Publicado: (2015)

Local injection of high-molecular hyaluronan promotes wound healing in old rats by increasing angiogenesis
por: Huang, Luying, et al.
Publicado: (2017)

Hydrogen sulfide in ageing, longevity and disease
por: Wilkie, Stephen E., et al.
Publicado: (2021)

Risk prediction for sporadic Alzheimer's disease using genetic risk score in the Han Chinese population
por: Xiao, Qianyi, et al.
Publicado: (2015)

Amyloid accumulation is a late event in sporadic Alzheimer's disease-like pathology in nontransgenic rats
por: Stefanova, Natalia A., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_cgvtqncpb985m362vlgcj3h2ot