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NADH autofluorescence, a new metabolic biomarker for cancer stem cells: Identification of Vitamin C and CAPE as natural products targeting “stemness”

Here, we assembled a broad molecular “tool-kit” to interrogate the role of metabolic heterogeneity in the propagation of cancer stem-like cells (CSCs). First, we subjected MCF7 cells to “metabolic fractionation” by flow cytometry, using fluorescent mitochondrial probes to detect PCG1α activity, as w...

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Detalles Bibliográficos
Autores principales:	Bonuccelli, Gloria, De Francesco, Ernestina Marianna, de Boer, Rianne, Tanowitz, Herbert B., Lisanti, Michael P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400535/ https://www.ncbi.nlm.nih.gov/pubmed/28223550 http://dx.doi.org/10.18632/oncotarget.15400

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