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Polymorphisms of ESR1, UGT1A1, HCN1, MAP3K1 and CYP2B6 are associated with the prognosis of hormone receptor-positive early breast cancer

In this study, we investigated whether single nucleotide polymorphisms (SNPs) identified by genome-wide association study (GWAS) (MAP3K1, FGFR2, TNRC9, HCN1, and 5p12), and SNPs involved in the metabolism of estrogen (CYP19, COMT, ESR1, and UGT1A1), tamoxifen (CYP2C9, CYP2C19, CYP3A5, and CYP2D6), a...

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Detalles Bibliográficos
Autores principales: Kuo, Sung-Hsin, Yang, Shi-Yi, You, San-Lin, Lien, Huang-Chun, Lin, Ching-Hung, Lin, Po-Han, Huang, Chiun-Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400556/
https://www.ncbi.nlm.nih.gov/pubmed/28178648
http://dx.doi.org/10.18632/oncotarget.14995

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