Afatinib radiosensitizes head and neck squamous cell carcinoma cells by targeting cancer stem cells

The dismal prognosis of locally advanced and metastatic squamous cell carcinoma of the head and neck (HNSCC) is primarily due to the development of resistance to chemoradiation therapy (CRT). Deregulation of Epidermal Growth Factor Receptor (EGFR) signaling is involved in HNSCC pathogenesis by regul...

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Detalles Bibliográficos
Autores principales: Macha, Muzafar A, Rachagani, Satyanarayana, Qazi, Asif Khurshid, Jahan, Rahat, Gupta, Suprit, Patel, Anery, Seshacharyulu, Parthasarathy, Lin, Chi, Li, Sicong, Wang, Shuo, Verma, Vivek, Kishida, Shosei, Kishida, Michiko, Nakamura, Norifumi, Kibe, Toshiro, Lydiatt, William M, Smith, Russell B, Ganti, Apar K, Jones, Dwight T, Batra, Surinder K, Jain, Maneesh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400558/
https://www.ncbi.nlm.nih.gov/pubmed/28423495
http://dx.doi.org/10.18632/oncotarget.15468

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