Drp1-dependent mitophagy protects against cisplatin-induced apoptosis of renal tubular epithelial cells by improving mitochondrial function

Cisplatin chemotherapy often causes acute kidney injury (AKI) in cancer patients. There is increasing evidence that mitochondrial dysfunction plays an important role in cisplatin-induced nephrotoxicity. Degradation of damaged mitochondria is carried out by mitophagy. Although mitophagy is considered...

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Detalles Bibliográficos
Autores principales: Zhao, Chuanyan, Chen, Zhuyun, Qi, Jia, Duan, Suyan, Huang, Zhimin, Zhang, Chengning, Wu, Lin, Zeng, Ming, Zhang, Bo, Wang, Ningning, Mao, Huijuan, Zhang, Aihua, Xing, Changying, Yuan, Yanggang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400560/
https://www.ncbi.nlm.nih.gov/pubmed/28423497
http://dx.doi.org/10.18632/oncotarget.15470

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