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The PIAS3-Smurf2 sumoylation pathway suppresses breast cancer organoid invasiveness

Tumor metastasis profoundly reduces the survival of breast cancer patients, but the mechanisms underlying breast cancer invasiveness and metastasis are incompletely understood. Here, we report that the E3 ubiquitin ligase Smurf2 acts in a sumoylation-dependent manner to suppress the invasive behavio...

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Detalles Bibliográficos
Autores principales:	Chandhoke, Amrita Singh, Chanda, Ayan, Karve, Kunal, Deng, Lili, Bonni, Shirin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400561/ https://www.ncbi.nlm.nih.gov/pubmed/28423498 http://dx.doi.org/10.18632/oncotarget.15471

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