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Epigenetic silencing of miR-520c leads to induced S100A4 expression and its mediated colorectal cancer progression
The S100 calcium-binding protein A4 (S100A4) induces epithelial mesenchymal transition, migration, invasion, angiogenesis and metastasis. Its induced expression in several cancer types correlates with poor prognosis. Apart from the functional and transcriptional regulatory aspects of S100A4, its pos...
Autores principales: | Mudduluru, Giridhar, Ilm, Katharina, Fuchs, Steffen, Stein, Ulrike |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400567/ https://www.ncbi.nlm.nih.gov/pubmed/28423501 http://dx.doi.org/10.18632/oncotarget.15499 |
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