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Differential expression of M3 muscarinic receptors in progressive colon neoplasia and metastasis

M3 muscarinic receptor (M3R) activation promotes colon cancer cell proliferation, migration, and invasion in vitro. Although over-expression of CHRM3, the gene encoding M3R, is reported in primary colon cancers, expression of M3R itself has not been studied in colon neoplasia. We compared M3R expres...

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Detalles Bibliográficos
Autores principales: Cheng, Kunrong, Shang, Aaron C., Drachenberg, Cinthia B., Zhan, Min, Raufman, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400569/
https://www.ncbi.nlm.nih.gov/pubmed/28416748
http://dx.doi.org/10.18632/oncotarget.15500