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Annonaceous acetogenins mediated up-regulation of Notch2 exerts growth inhibition in human gastric cancer cells in vitro

BACKGROUND: Gastric cancer (GC) is a global health problem because of limited treatments and poor prognosis. Annonaceous acetogenins (ACGs) has been reported to exert anti-tumorigenic effects in cancer, yet the mechanism underlying its effects on GC remains largely unknown. Notch signaling plays a c...

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Detalles Bibliográficos
Autores principales: Li, Yan, Ye, Jianbin, Chen, Zhongbiao, Wen, Junjie, Li, Fei, Su, Pengpeng, Lin, Yanqing, Hu, Bingxin, Wu, Danlin, Ning, Lijun, Xue, Qi, Gu, Hongxiang, Ning, Yunshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400572/
https://www.ncbi.nlm.nih.gov/pubmed/28416750
http://dx.doi.org/10.18632/oncotarget.15502