Histone lysine methyltransferase G9a is a novel epigenetic target for the treatment of hepatocellular carcinoma

Histone H3 lysine 9 dimethylation (H3K9me2) is mainly regulated by the histone lysine methyltransferase G9a and is associated with the repression of transcription. However, both the role of G9a and the significance of H3K9me2 in hepatocellular carcinoma (HCC) cells remain unclear. In this study, we...

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Detalles Bibliográficos
Autores principales: Yokoyama, Masayuki, Chiba, Tetsuhiro, Zen, Yoh, Oshima, Motohiko, Kusakabe, Yuko, Noguchi, Yoshiko, Yuki, Kaori, Koide, Shuhei, Tara, Shiro, Saraya, Atsunori, Aoyama, Kazumasa, Mimura, Naoya, Miyagi, Satoru, Inoue, Masanori, Wakamatsu, Toru, Saito, Tomoko, Ogasawara, Sadahisa, Suzuki, Eiichiro, Ooka, Yoshihiko, Tawada, Akinobu, Otsuka, Masayuki, Miyazaki, Masaru, Yokosuka, Osamu, Iwama, Atsushi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400586/
https://www.ncbi.nlm.nih.gov/pubmed/28423509
http://dx.doi.org/10.18632/oncotarget.15528

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