miR-106b-5p promotes renal cell carcinoma aggressiveness and stem-cell-like phenotype by activating Wnt/β-catenin signalling

PURPOSE: To examine the role of miR-106b-5p in regulating the cancer stem-cell-like phenotype in clear cell renal cell carcinomas (ccRCC). EXPERIMENTAL DESIGN: Real-time PCR was performed to evaluate miR-106b-5p levels in ccRCC cell lines and patients specimens. A series of in vivo and in vitro assa...

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Detalles Bibliográficos
Autores principales: Lu, Jun, Wei, Jin-Huan, Feng, Zi-Hao, Chen, Zhen-Hua, Wang, Yong-Qian, Huang, Yong, Fang, Yong, Liang, Yan-Ping, Cen, Jun-Jie, Pan, Yi-Hui, Liao, Bing, Chen, Wen-Fang, Chen, Wei, Luo, Jun-Hang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400598/
https://www.ncbi.nlm.nih.gov/pubmed/28423523
http://dx.doi.org/10.18632/oncotarget.15591

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