ONC201 activates ER stress to inhibit the growth of triple-negative breast cancer cells

ONC201 was previously identified as a first-in-class antitumor agent and small-molecule inducer of the TRAIL (tumor necrosis factor-related apoptosis-inducing ligand) gene that induces apoptosis in cancer cells. ONC201 has a safety profile and is currently in phase II clinical trials for the treatme...

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Detalles Bibliográficos
Autores principales: Yuan, Xun, Kho, Dhonghyo, Xu, Jing, Gajan, Ambikai, Wu, Kongming, Wu, Gen Sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400611/
https://www.ncbi.nlm.nih.gov/pubmed/28423492
http://dx.doi.org/10.18632/oncotarget.15451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400611/
https://www.ncbi.nlm.nih.gov/pubmed/28423492
http://dx.doi.org/10.18632/oncotarget.15451

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