Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature

BACKGROUND: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. As many clinical cases have reported, it may be associated with hepatitis C virus (HCV) infection. Antiviral therapy can be various. CASE SUMMARY: We report a case of patient with chronic HCV infection...

Descripción completa

Detalles Bibliográficos
Autores principales: Weng, Qinjie, Li, Xiao, Ren, Hong, Xie, Jingyuan, Pan, Xiaoxia, Xu, Jing, Chen, Nan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400664/
https://www.ncbi.nlm.nih.gov/pubmed/28223549
http://dx.doi.org/10.18632/oncotarget.15397
_version_ 1783230897692082176
author Weng, Qinjie
Li, Xiao
Ren, Hong
Xie, Jingyuan
Pan, Xiaoxia
Xu, Jing
Chen, Nan
author_facet Weng, Qinjie
Li, Xiao
Ren, Hong
Xie, Jingyuan
Pan, Xiaoxia
Xu, Jing
Chen, Nan
author_sort Weng, Qinjie
collection PubMed
description BACKGROUND: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. As many clinical cases have reported, it may be associated with hepatitis C virus (HCV) infection. Antiviral therapy can be various. CASE SUMMARY: We report a case of patient with chronic HCV infection and MN, who presented with was proteinuria. He was treated with ledipasvir and sofosbuvir (Harvoni; Gilead Sciences, Foster City, CA) and was found to be virus-free. CONCLUSION: We have reported this case to provide insight into whether Ledipasvir-Sofosbuvir should be administered for HCV-related glomerulonephritis.
format Online
Article
Text
id pubmed-5400664
institution National Center for Biotechnology Information
language English
publishDate 2017
publisher Impact Journals LLC
record_format MEDLINE/PubMed
spelling pubmed-54006642017-05-03 Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature Weng, Qinjie Li, Xiao Ren, Hong Xie, Jingyuan Pan, Xiaoxia Xu, Jing Chen, Nan Oncotarget Case Report BACKGROUND: Membranous nephropathy (MN) is the most common cause of nephrotic syndrome in adults. As many clinical cases have reported, it may be associated with hepatitis C virus (HCV) infection. Antiviral therapy can be various. CASE SUMMARY: We report a case of patient with chronic HCV infection and MN, who presented with was proteinuria. He was treated with ledipasvir and sofosbuvir (Harvoni; Gilead Sciences, Foster City, CA) and was found to be virus-free. CONCLUSION: We have reported this case to provide insight into whether Ledipasvir-Sofosbuvir should be administered for HCV-related glomerulonephritis. Impact Journals LLC 2017-02-16 /pmc/articles/PMC5400664/ /pubmed/28223549 http://dx.doi.org/10.18632/oncotarget.15397 Text en Copyright: © 2017 Weng et al. http://creativecommons.org/licenses/by/3.0/ This article is distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0/) (CC-BY), which permits unrestricted use and redistribution provided that the original author and source are credited.
spellingShingle Case Report
Weng, Qinjie
Li, Xiao
Ren, Hong
Xie, Jingyuan
Pan, Xiaoxia
Xu, Jing
Chen, Nan
Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature
title Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature
title_full Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature
title_fullStr Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature
title_full_unstemmed Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature
title_short Membranous nephropathy associated with hepatitis C virus infection treated with corticosteroids and Ledipasvir-Sofosbuvir: a case report and review of literature
title_sort membranous nephropathy associated with hepatitis c virus infection treated with corticosteroids and ledipasvir-sofosbuvir: a case report and review of literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400664/
https://www.ncbi.nlm.nih.gov/pubmed/28223549
http://dx.doi.org/10.18632/oncotarget.15397
work_keys_str_mv AT wengqinjie membranousnephropathyassociatedwithhepatitiscvirusinfectiontreatedwithcorticosteroidsandledipasvirsofosbuviracasereportandreviewofliterature
AT lixiao membranousnephropathyassociatedwithhepatitiscvirusinfectiontreatedwithcorticosteroidsandledipasvirsofosbuviracasereportandreviewofliterature
AT renhong membranousnephropathyassociatedwithhepatitiscvirusinfectiontreatedwithcorticosteroidsandledipasvirsofosbuviracasereportandreviewofliterature
AT xiejingyuan membranousnephropathyassociatedwithhepatitiscvirusinfectiontreatedwithcorticosteroidsandledipasvirsofosbuviracasereportandreviewofliterature
AT panxiaoxia membranousnephropathyassociatedwithhepatitiscvirusinfectiontreatedwithcorticosteroidsandledipasvirsofosbuviracasereportandreviewofliterature
AT xujing membranousnephropathyassociatedwithhepatitiscvirusinfectiontreatedwithcorticosteroidsandledipasvirsofosbuviracasereportandreviewofliterature
AT chennan membranousnephropathyassociatedwithhepatitiscvirusinfectiontreatedwithcorticosteroidsandledipasvirsofosbuviracasereportandreviewofliterature

Ejemplares similares