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Novel linkage disequilibrium clustering algorithm identifies new lupus genes on meta-analysis of GWAS datasets
Systemic lupus erythematosus (SLE) is a complex disorder. Genetic association studies of complex disorders suffer from the following three major issues: phenotypic heterogeneity, false positive (type I error), and false negative (type II error) results. Hence, genes with low to moderate effects are...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Springer Berlin Heidelberg
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5400794/ https://www.ncbi.nlm.nih.gov/pubmed/28246883 http://dx.doi.org/10.1007/s00251-017-0976-8 |