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Mega-Trials: Methodological Issues and Clinical Implications
A recent development of the therapeutic trial has been the mega-trial: a large, simple randomised trial analysed on an 'intention to treat' basis. Mega-trials have advantages in terms of increased statistical power, but also raise several new questions of interpretation. In mega-trials, ra...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Royal College of Physicians of London
1995
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401292/ https://www.ncbi.nlm.nih.gov/pubmed/7595900 |