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Blockade of Neutrophil’s Chemokine Receptors CXCR1/2 Abrogate Liver Damage in Acute-on-Chronic Liver Failure

BACKGROUND: Neutrophils serve as critical players in the pathogenesis of liver diseases. Chemokine receptors CXCR1 and CXCR2 are required for neutrophil chemotaxis to the site of inflammation/injury and are crucial in hepatic inflammatory response. However, key mechanism of neutrophil-mediated liver...

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Detalles Bibliográficos
Autores principales:	Khanam, Arshi, Trehanpati, Nirupma, Riese, Peggy, Rastogi, Archana, Guzman, Carlos Alberto, Sarin, Shiv Kumar
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5401894/ https://www.ncbi.nlm.nih.gov/pubmed/28484461 http://dx.doi.org/10.3389/fimmu.2017.00464

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