Cargando…
MiR-146b is down-regulated during the chondrogenic differentiation of human bone marrow derived skeletal stem cells and up-regulated in osteoarthritis
Articular cartilage injury can result in chondrocyte loss and diminishment of specialised extracellular matrix, which can progress to an osteoarthritic (OA) phenotype. Stem cells have emerged as a favourable approach for articular cartilage regeneration. Identification of miRNAs which influence stem...
Autores principales: | Budd, Emma, de Andrés, María C., Sanchez-Elsner, Tilman, Oreffo, Richard O. C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402270/ https://www.ncbi.nlm.nih.gov/pubmed/28436462 http://dx.doi.org/10.1038/srep46704 |
Ejemplares similares
-
MicroRNA-146a Regulates Human Foetal Femur Derived Skeletal Stem Cell Differentiation by Down-Regulating SMAD2 and SMAD3
por: Cheung, Kelvin S. C., et al.
Publicado: (2014) -
Chondrogenic potential of human articular chondrocytes and skeletal stem cells: A comparative study
por: Li, Siwei, et al.
Publicado: (2014) -
The Potential of microRNAs for Stem Cell-based Therapy for Degenerative Skeletal Diseases
por: Budd, Emma, et al.
Publicado: (2017) -
Icariin-Loaded Hydrogel Regulates Bone Marrow Mesenchymal Stem Cell Chondrogenic Differentiation and Promotes Cartilage Repair in Osteoarthritis
por: Zhu, Yuefeng, et al.
Publicado: (2022) -
CD146(+) skeletal stem cells from growth plate exhibit specific chondrogenic differentiation capacity in vitro
por: Wu, Ying-Xing, et al.
Publicado: (2017)