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The Membrane-Proximal Region of C–C Chemokine Receptor Type 5 Participates in the Infection of HIV-1

The initial infection and transmission of HIV-1 requires C–C chemokine receptor type 5 (CCR5). Here, we report that the membrane-proximal region (MPR, aa 22–38) of CCR5 participates in the infection of HIV-1. First, MPR-specific antibodies elicited in mice dose-dependently inhibited the infection of...

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Detalles Bibliográficos
Autores principales:	Tan, Yue, Tong, Pei, Wang, Junyi, Zhao, Lei, Li, Jing, Yu, Yang, Chen, Ying-Hua, Wang, Ji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2017
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402540/ https://www.ncbi.nlm.nih.gov/pubmed/28484468 http://dx.doi.org/10.3389/fimmu.2017.00478

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