A Versatile Tumor Gene Deletion System Reveals a Crucial Role for FGFR1 in Breast Cancer Metastasis

RCAS avian viruses have been used to deliver oncogene expression and induce tumors in transgenic mice expressing the virus receptor TVA. Here we report the generation and characterization of a novel RCAS-Cre-IRES-PyMT (RCI-PyMT) virus designed to specifically knockout genes of interest in tumors gen...

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Detalles Bibliográficos
Autores principales: Wang, Wei, Meng, Yanling, Dong, Bingning, Dong, Jie, Ittmann, Michael M., Creighton, Chad J., Lu, Yang, Zhang, Hong, Shen, Tao, Wang, Jianghua, Rowley, David R., Li, Yi, Chen, Fengju, Moore, David D., Yang, Feng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2017
Materias:
Original article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402631/
https://www.ncbi.nlm.nih.gov/pubmed/28433771
http://dx.doi.org/10.1016/j.neo.2017.03.003

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402631/
https://www.ncbi.nlm.nih.gov/pubmed/28433771
http://dx.doi.org/10.1016/j.neo.2017.03.003

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