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Neuron-restrictive silencer factor–mediated downregulation of μ-opioid receptor contributes to the reduced morphine analgesia in bone cancer pain

Bone cancer pain has been reported to have unique mechanisms and is resistant to morphine treatment. Recent studies have indicated that neuron-restrictive silencer factor (NRSF) plays a crucial role in modulating the expression of the μ-opioid receptor (MOR) gene. The present study elucidates the re...

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Detalles Bibliográficos
Autores principales:	Zhu, Chao, Tang, Jun, Ding, Tan, Chen, Lei, Wang, Wei, Mei, Xiao-Peng, He, Xiao-Tao, Wang, Wen, Zhang, Li-Dong, Dong, Yu-Lin, Luo, Zhuo-Jing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer 2017
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402709/ https://www.ncbi.nlm.nih.gov/pubmed/28415063 http://dx.doi.org/10.1097/j.pain.0000000000000848

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