Genomic analysis of globally diverse Mycobacterium tuberculosis strains provides insights into emergence and spread of multidrug resistance

Multidrug-resistant tuberculosis (MDR-TB), caused by drug resistant strains of Mycobacterium tuberculosis, is an increasingly serious problem worldwide. In this study, we examined a dataset of 5,310 M. tuberculosis whole genome sequences from five continents. Despite great diversity with respect to...

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Detalles Bibliográficos
Autores principales: Manson, Abigail L., Cohen, Keira A., Abeel, Thomas, Desjardins, Christopher A., Armstrong, Derek T., Barry, Clifton E., Brand, Jeannette, Chapman, Sinéad B., Cho, Sang-Nae, Gabrielian, Andrei, Gomez, James, Jodals, Andreea M., Joloba, Moses, Jureen, Pontus, Lee, Jong Seok, Malinga, Lesibana, Maiga, Mamoudou, Nordenberg, Dale, Noroc, Ecaterina, Romancenco, Elena, Salazar, Alex, Ssengooba, Willy, Velayati, A. A., Winglee, Kathryn, Zalutskaya, Aksana, Via, Laura E., Cassell, Gail H., Dorman, Susan E., Ellner, Jerrold, Farnia, Parissa, Galagan, James E., Rosenthal, Alex, Crudu, Valeriu, Homorodean, Daniela, Hsueh, Po-Ren, Narayanan, Sujatha, Pym, Alexander S., Skrahina, Alena, Swaminathan, Soumya, Van der Walt, Martie, Alland, David, Bishai, William R., Cohen, Ted, Hoffner, Sven, Birren, Bruce W., Earl, Ashlee M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5402762/
https://www.ncbi.nlm.nih.gov/pubmed/28092681
http://dx.doi.org/10.1038/ng.3767

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